RFA1 Rabbit Polyclonal Antibody, 20ul NGS Oligos this encoded protein does not

this encoded protein does not seem to have PPIase/rotamase activity

Polymorphisms in this gene may also influence the severity of deafness caused by mitochondrial 12S ribosomal RNA mutations

with its amino acid sequence being highly conserved between members and among divergent species

an adaptor protein involved in the downstream signaling of cytokine receptors

|tissue specificity:Abundantly expressed in heart and pancreas

RFA1 Rabbit Polyclonal Antibody, 20ul NGS Oligos this encoded protein does notIt participates in a very early step in initiation. RP A is a single stranded DNA binding protein. Absolutely required for simian virus 40 DNA replication in vitro. PTM: Phosphorylated upon DNA damage probably by ATM or ATR. Belongs to the replication factor A protein 1 family. subunit: Heterotrimer of 70 32 and 14 kDa chains. The DNA binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.